The project

The SiMBiT project will develop a bio-electronic smart system leveraging on an existing lab-based proof-of-concept that can perform single-molecule detection of both proteins and DNA bio-markers.

Specifically, the SiMBiT activities will develop the lab-based device into a cost-effective portable multiplexing array prototype that integrates, with a modular approach, novel materials and standard components/interfaces.

The SiMBiT platform exhibits enhanced sensing capabilities: specificity towards both genomic and protein markers along with single-molecule detection limits and time-to results within two hours.

This makes the SiMBiT prototype the world best performing bio-electronic sensing system ever.

The platform is also single-use and cost-effective and can work in low-resource settings.

The SiMBiT field-effect sensing system will be fabricated by means of future mass manufacturable, large-area compatible, scalable techniques such as printing and other direct-writing processes.

The SiMBiT prototype will demonstrate, for first time, a matrix of up to 96 bio-electronic sensors and a Si IC chip for the processing of all data coming from the matrix, multiplexing single-molecule detection. As the Si IC pins are limited the chip area is reduced and its cost minimized, enabling a single-use assay plate.

SiMBiT will apply the multiplexing single molecule technology to the early detection of human pancreatic neoplasms in a well-defined clinical context, performing simultaneous analysis of genomic and protein markers with a minimal sample volume, reduced costs and reduced time-to-results

News

  • PARTICIPATION TO THE WORLD CONGRESS ON BIOSENSORS IN KOREA IN NOVEMBER 2020 03 August 2020

    We are pleased that SiMBiT project coordinator Luisa Torsi will be one of the plenary speaker at the...

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  • SiMBiT’S DEMONSTRATION OF THE SINGLE MOLECULE DETECTION THANKS TO SiMoT TECHNOLOGY 09 July 2020

    At the beginning of this year, part of the SiMBiT consortium published a paper on current...

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  • SiMBiT – First year activities and achievments 11 March 2020

    Already 14 months have passed since the beginning of the SiMBiT project. Now that the first year...

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