The project

The SiMBiT project will develop a bio-electronic smart system leveraging on an existing lab-based proof-of-concept that can perform single-molecule detection of both proteins and DNA bio-markers.

Specifically, the SiMBiT activities will develop the lab-based device into a cost-effective portable multiplexing array prototype that integrates, with a modular approach, novel materials and standard components/interfaces.

The SiMBiT platform exhibits enhanced sensing capabilities: specificity towards both genomic and protein markers along with single-molecule detection limits and time-to results within two hours.

This makes the SiMBiT prototype the world best performing bio-electronic sensing system ever.

The platform is also single-use and cost-effective and can work in low-resource settings.

The SiMBiT field-effect sensing system will be fabricated by means of future mass manufacturable, large-area compatible, scalable techniques such as printing and other direct-writing processes.

The SiMBiT prototype will demonstrate, for first time, a matrix of up to 96 bio-electronic sensors and a Si IC chip for the processing of all data coming from the matrix, multiplexing single-molecule detection. As the Si IC pins are limited the chip area is reduced and its cost minimized, enabling a single-use assay plate.

SiMBiT will apply the multiplexing single molecule technology to the early detection of human pancreatic neoplasms in a well-defined clinical context, performing simultaneous analysis of genomic and protein markers with a minimal sample volume, reduced costs and reduced time-to-results

News

  • Kick-off Meeting in Bari January 10th and 11th 2019 01 January 2019

    Launching days for the SiMBiT project, University of Bari received all the partners of the project for the...

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  • Participation to E-MRS exhibition held in Nice on May 28th to 30 th 2019 01 February 2019

    This year to the European Materials Research Society, 80 international exhibitors will display a full...

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  • Participation to European Commission workshop “Smart Bioelectronic and Wearable Systems” held in Brussels on October 22nd and 23rd 2019 07 October 2019

    This European workshop presents breakthroughs and innovations in smart bioelectronics and flexible &...

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