The single molecule bio-electronic
smart system array for clinical testing

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sensing system
Single-molecule detection - sensitive

Context of the project

ELISA after more than 40 years since its discovery, is still the most popular multiplexing assay to quantify protein bio-markers despite the performance level limited by multiple assay steps, low sensitivity and low dynamic range.

Digitizing biomarkers analysis by quantifying them at the single-molecule level is the new frontier for advancing the science of precision health. Such an occurrence will enormously enhance their ability of curing diseases by supporting better prognosis and permitting the application of precise treatment methods. An enormous improvement in the quality of life and longevity of the population for generations to come is foreseen along with a reduction of health care expenses.

The disruptive bio-electronic smart system developed in SiMBiT will open to a massive use of high-throughput array-based assay not only in clinical laboratory analysis, but also in point-of-care and low resources settings.


  • Postpone of EXNER event 2021 - Luisa Torsi Lecture 10 December 2021

    We had previously announced you the event surrounding the awarding of the Wilhelm Exner Medals in 2020...

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  • Luisa Torsi Speaker at the EXNER LECTURES 2021 29 October 2021

     Luisa Torsi, Project coordinator of SiMBiT project and laureate from 2020 of the Exner Medal 2021,...

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  • Advance on pancreatic cancer biomarkers detection 01 August 2021

    We are very proud of the ongoing work we have done and available online, offering the first ever...

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